A bacteriocin

Nisin (>900 IU/mg, contains min. 50% NaCl) – 5 g

Brand:
Cayman
CAS:
1414-45-5
Storage:
4
UN-No:
Non-Hazardous - /

Nisin A is a bacteriocin, a natural polycyclic antibacterial peptide.{27112} It is produced by the lactic acid bacterium L. lactis using uncommon amino acids, including lanthionine, and is a member of the class of antibiotics referred to as lantibiotics.{27113} Nisin A is particularly effective against Gram-positive bacteria and is commonly used as a food preservative.{27112,27114} Lantibiotics, including nisin A, form complexes with membrane-bound peptidoglycan precursors on the surface of bacteria, resulting in pore formation and cell death.{27112,27114}  

 

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Description

A bacteriocin, a natural polycyclic antibacterial peptide, also called a lantibiotic; particularly effective against Gram-positive bacteria and commonly used as a food preservative

Formal name: L-isoleucyl-(Z)-2,3-didehydro-2-aminobutanoyl-D-cysteinyl-L- isoleucyl-2,3-didehydroalanyl-L-leucyl-L-cysteinyl-threo-3- mercapto-D-2-aminobutanoyl-L-prolylglycyl-L-cysteinyl-L-lysyl- threo-3-mercapto-D-2-aminobutanoylglycyl-L-alanyl-L-leucyl-L- methionylglycyl-L-cysteinyl-L-asparaginyl-L-methionyl-L-lysyl- threo-3-mercapto-D-2-aminobutanoyl-L-alanyl-threo-3-mercapto- D-2-aminobutanoyl-L-cysteinyl-L-histidyl-L-cysteinyl-L-seryl- L-isoleucyl-L-histidyl-L-valyl-2,3-didehydroalanyl- L-lysine, cyclic (3→7),(8→11),(13→19),(23→26),(25→28)-pentakis(sulfide)

Synonyms:  Ambicin N

Molecular weight: 3,354.10

CAS: 1414-45-5

Purity:

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Polypeptides||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Peptides||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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