An ionophorous antibiotic that preferentially forms complexes with monovalent cations for lipid-soluble transport across membrane bilayers; active against Gram-positive bacteria such as Micrococcus

Monensin (sodium salt) – 1 g

Brand:
Cayman
CAS:
22373-78-0
Storage:
-20
UN-No:
De Minimis - 3462 / 6.1

Monensin is a naturally occuring ionophorous antibiotic that preferentially forms complexes with monovalent cations to enable transport across lipid membranes.{26941} Through its ability to affect pH and the sodium-potassium balance of a cell, monensin can induce cell death in Gram-positive bacteria such as Micrococcus, Bacillus, and Staphylococcus (MICs = 1-12.5 µg/ml), reduce proliferation of P. falciparum and Coccicdium protozoa, and also prevent replication of certain viruses.{26941}  

 

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Description

An ionophorous antibiotic that preferentially forms complexes with monovalent cations for lipid-soluble transport across membrane bilayers; active against Gram-positive bacteria such as Micrococcus, Bacillus, and Staphylococcus (MICs = 1-12.5 µg/ml), of P. falciparum and Coccicdium protozoa, and certain viruses

Formal name: 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-hydroxymethyl-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid, monosodium salt

Synonyms:  Monensin A|NSC 343257

Molecular weight: 692.9

CAS: 22373-78-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Antivirals||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Parasitic Diseases|Malaria||Research Area|Infectious Disease|Viral Diseases

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