A derivative of testosterone and ethisterone that binds androgen receptors and sex hormone-binding globulin causing a 3-fold increase in free testosterone; possesses weak androgenic effects and inhibits the production of gonadotropins

Danazol – 250 mg

Brand:
Cayman
CAS:
17230-88-5
Storage:
-20
UN-No:
Non-Hazardous - /

Danazol is a derivative of testosterone (Item No. 15645) and ethisterone that can bind to androgen receptors and sex hormone-binding globulin causing a 3-fold increase in free testosterone.{20422,26901,26903} It possesses weak androgenic effects and inhibits the production of gonadotropins.{26904} It has been used to address symptoms of endometriosis and to inhibit the growth of endocrine-responsive pancreatic and breast cancer cells but has also been linked to the development of ovarian cancer.{26901,26904,26902}  

 

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Description

A derivative of testosterone and ethisterone that binds androgen receptors and sex hormone-binding globulin causing a 3-fold increase in free testosterone; possesses weak androgenic effects and inhibits the production of gonadotropins

Formal name: pregna-2,4-dien-20-yno[2,3-d]isoxazol-17α-ol

Synonyms:  Danocrine|Ladogal|NSC 270916|WIN 17,757

Molecular weight: 337.5

CAS: 17230-88-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cancer||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Androgens

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