A muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum; inhibits a component of store-operated calcium entry (SOCE) that is coupled to the skeletal muscle ryanodine receptor

Azumolene (sodium salt) – 5 mg

Brand:
Cayman
CAS:
105336-14-9
Storage:
-20
UN-No:
Non-Hazardous - /

Azumolene is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum.{27018,27021} It inhibits a component of store-operated calcium entry (SOCE) that is coupled to the skeletal muscle ryanodine receptor, with 20 µM azumolene causing a 70% reduction in SOCE in myotubes.{27020,27019} Azumolene has utility in countering muscle dysfunction associated with malignant hyperthermia.{27019}  

 

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Description

A muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum; inhibits a component of store-operated calcium entry (SOCE) that is coupled to the skeletal muscle ryanodine receptor, with 20 µM azumolene causing a 70% reduction in SOCE in myotubes

Formal name: 1-[[[5-(4-bromophenyl)-2-oxazolyl]methylene]amino]-2,4-imidazolidinedione, monosodium salt

Synonyms:  EU4093

Molecular weight: 371.1

CAS: 105336-14-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Neuroscience

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