The reduced form of α-lipoic acid that acts as a general antioxidant at concentrations ranging from 0.01-0.5 mM; at 50-100 µM

Dihydrolipoic Acid – 100 mg

Brand:
Cayman
CAS:
462-20-4
Storage:
-20
UN-No:
Non-Hazardous - /

Dihydrolipoic acid (DHLA) is a dithiol-containing carboxylic acid that is the reduced form of α-lipoic acid (Item No. 10005728). It acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including hydroxyl radicals, peroxynitirite, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.{26768} At concentrations of 50-100 µM, DHLA triggers apoptosis of mouse embryonic stem cells and human cancer cells, suppressing proliferation.{26767}  

 

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Description

The reduced form of α-lipoic acid that acts as a general antioxidant at concentrations ranging from 0.01-0.5 mM; at 50-100 µM, triggers apoptosis of mouse embryonic stem cells and human cancer cells, suppressing proliferation

Formal name: 6,​8-​dimercapto-octanoic acid

Synonyms:  DHLA

Molecular weight: 208.3

CAS: 462-20-4

Purity: ≥95%

Formulation: A neat oil

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Stem Cell Research|Proliferation||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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