A partial agonist of α2A-

TDIQ (hydrochloride) – 1 mg

Brand:
Cayman
CAS:
15052-05-8
Storage:
-20
UN-No:
Non-Hazardous - /

TDIQ (hydrochloride) is an analytical reference standard that is classified as a phenylalkylamine. It is related in structure to amphetamines but does not appear to affect locomotor activity.{30507} TDIQ is a partial agonist of α2A-, α2B-, and α2C-adrenergic receptors (Kis = 75, 95, and 65 nM, respectively) but has low affinity for dopamine or serotonin receptors and does not affect catecholamine release in rodent brain synaptosomes.{30507} Drug discrimination studies in rats indicate that it can serve as a discriminative stimulus, generalizing to cocaine (Item Nos. 16186, ISO60176) and partially to 3,4-MDMA (Item Nos. 13971, ISO60190) and methcathinone (Item No. 11709), but not to amphetamine (Item Nos. 15797, 15650).{30507} TDIQ has also been shown to exhibit anxiolytic and anorectic effects in rodent models.{30507} This product is intended for forensic and research purposes.  

 

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Description

A partial agonist of α2A-, α2B-, and α2C-adrenergic receptors (Kis = 75, 95, and 65 nM, respectively) that exhibits anxiolytic and anorectic effects in rodent models; acts as a discriminative stimulus, generalizing to cocaine in rat drug discrimination studies

Formal name: 5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinoline, monohydrochloride

Synonyms:  6,7-Methylenedioxy-1,2,3,4-tetrahydroisoquinoline|MDTHIQ

Molecular weight: 213.7

CAS: 15052-05-8

Purity: ≥95%

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Drugs of Abuse||Research Area|Forensic Chemistry & Toxicology|Hallucinogens|Phenethylamines||Research Area|Forensic Chemistry & Toxicology|Stimulants|Phenethylamines

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