A steroid hormone produced in the cortex of the adrenal glands that binds to both glucocorticoid and mineralocorticoid receptors; also is the precursor to aldosterone synthesis

Corticosterone – 500 mg

Brand:
Cayman
CAS:
50-22-6
Storage:
-20
UN-No:
Non-Hazardous - /

Corticosterone is a steroid hormone produced in the cortex of the adrenal glands that binds to both glucocorticoid and mineralocorticoid receptors.{26042} It is produced in response to ACTH (corticotropic hormone) and is the precursor to aldosterone synthesis.{19056} Since the production of glucocorticoids is increased by stress, it is often used as a biomarker of stress.{11468} Plasma corticosterone levels have a circadian variation and corticosterone may be important in the regulation of the sleep-wake cycle.{11469,11480}  

 

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Description

A steroid hormone produced in the cortex of the adrenal glands that binds to both glucocorticoid and mineralocorticoid receptors; also is the precursor to aldosterone synthesis

Formal name: 11β,21-dihydroxy-pregn-4-ene-3,20-dione

Synonyms:  11β,21-DHP|11β,21-dihydroxy Progesterone|17-deoxy Cortisol|NSC 9705

Molecular weight: 346.5

CAS: 50-22-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Glucocorticoids & Mineralocorticoids||Research Area|Neuroscience|Behavioral Neuroscience|Sleep & Biological Rhythms||Research Area|Neuroscience|Neuroendocrinology

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