A cephalosporin antibiotic with potent in vitro activity against streptococcal species

Cefotaxime (sodium salt) – 1 g

Brand:
Cayman
CAS:
64485-93-4
Storage:
-20
UN-No:
Non-Hazardous - /

Cefotaxime is a cephalosporin antibiotic with potent in vitro activity against streptococcal species, including S. aureus (IC50 = 2 µg/ml) and penicillin-resistant S. pneumoniae.{25856} It is also effective against a wide range of other β-lactamase-producing bacterial species (MIC90s = 0.01 – 130 µg/ml).{25856} Cefotaxime acts by interfering with bacterial cell wall synthesis and has also been shown to be a competitive inhibitor of β-lactamase.{25971}  

 

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Description

A cephalosporin antibiotic with potent in vitro activity against streptococcal species, including S. aureus (IC50 = 2 µg/ml) and penicillin-resistant S. pneumonia and also effective against a wide range of other β-lactamase-producing bacterial species (MIC90s = 0.01 – 130 µg/ml)

Formal name: (6R)-3-[(acetyloxy)methyl]-7R-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt

Synonyms: 

Molecular weight: 477.5

CAS: 64485-93-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Cephalosporins||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia

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