An antibiotic that inhibits DOXP reductoisomerase

Fosmidomycin (sodium salt) – 1 mg

Brand:
Cayman
CAS:
66508-37-0
Storage:
-20
UN-No:
Non-Hazardous - /

Fosmidomycin is an antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces that inhibits DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.{26496} Fosmidomycin is active against both Gram-negative and Gram-positive bacteria and the human malarial parasite P. falciparum (IC50 = 290-370 nM).{26495}  

 

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Description

An antibiotic that inhibits DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis; against both Gram-negative and Gram-positive bacteria and the human malarial parasite P. falciparum (IC50 = 290-370 nM)

Formal name: P-[3-(formylhydroxyamino)propyl]-phosphonic acid, monosodium salt

Synonyms:  Antibiotic FR31564|FR31564

Molecular weight: 205.1

CAS: 66508-37-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Parasitic Diseases|Malaria

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