An α2-adrenergic receptor agonist (Kd = 7.6 nM for rat cerebral cortex membranes) that has transient antihypertensive effects; used in managing opioid withdrawal symptoms during detoxification from heroin and methadone

Lofexidine (hydrochloride) – 1 g

Brand:
Cayman
CAS:
21498-08-8
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Lofexidine is an α2-adrenergic receptor agonist (Kd = 7.6 nM for rat cerebral cortex membranes) that has transient antihypertensive effects.{26103,26105} It is used in managing opioid withdrawal symptoms during detoxification from heroin (Item No. 9001543) and methadone.{26104,26101}  

 

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Description

An α2-adrenergic receptor agonist (Kd = 7.6 nM for rat cerebral cortex membranes) that has transient antihypertensive effects; used in managing opioid withdrawal symptoms during detoxification from heroin and methadone

Formal name: 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole, monohydrochloride

Synonyms: 

Molecular weight: 295.6

CAS: 21498-08-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Neuroscience|Behavioral Neuroscience|Addiction Research

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