A reversible

MMP Inhibitor II – 10 mg

Brand:
Cayman
CAS:
203915-59-7
Storage:
-20
UN-No:
Non-Hazardous - /

Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration.{16569} MMP Inhibitor II is a reversible, broad-range inhibitor of MMPs. It has been reported to inhibit MMP-1 (IC50 = 24 nM), MMP-3 (IC50 = 18.4 nM), MMP-7 (IC50 = 30 nM), and MMP-9 (IC50 = 2.7 nM).{25901}  

 

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Description

A reversible, broad-range inhibitor of MMP-1 (IC50 = 24 nM), MMP-3 (IC50 = 18.4 nM), MMP-7 (IC50 = 30 nM), and MMP-9 (IC50 = 2.7 nM)

Formal name: hexahydro-N-hydroxy-1,3-bis[(4-methoxyphenyl)sulfonyl]-5,5-dimethyl-2-pyrimidinecarboxamide

Synonyms:  Matrix Metalloproteinase Inhibitor II|NHDDPC|PG 117025|PGE 4410186

Molecular weight: 513.6

CAS: 203915-59-7

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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