A prodrug form of N-desethyl amodiaquine; active against several strains of P. falciparum in vitro (EC50s = 0.23-0.52 nM) and exhibits a synergistic effect when used in combination with N-desethyl amodiaquine; dose-dependently inhibits development of parasitemia in a mouse model of P. berghei infection

Amodiaquine – 50 mg

Brand:
Cayman
CAS:
86-42-0
Storage:
-20
UN-No:
Non-Hazardous - /

Amodiaquine is a prodrug form of the antimalarial compound N-desethyl amodiaquine (Item No. 20822).{26895,26896} It is active against several strains of P. falciparum in vitro (EC50s = 0.23-0.52 nM) and exhibits a synergistic effect when used in combination with N-desethyl amodiaquine.{26895} Amodiaquine dose-dependently inhibits development of parasitemia in a mouse model of P. berghei infection.{47585}  

 

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Description

A prodrug form of N-desethyl amodiaquine; active against several strains of P. falciparum in vitro (EC50s = 0.23-0.52 nM) and exhibits a synergistic effect when used in combination with N-desethyl amodiaquine; dose-dependently inhibits development of parasitemia in a mouse model of P. berghei infection

Formal name: 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-phenol

Synonyms:  Camoquine|Flavoquine|NSC 13453|SN 10751

Molecular weight: 355.9

CAS: 86-42-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases|Malaria

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