A natural flavonoid that has potent antioxidant and anti-inflammatory properties; acts as an antagonist of AhR

Galangin – 10 mg

Brand:
Cayman
CAS:
548-83-4
Storage:
-20
UN-No:
Non-Hazardous - /

Galangin is a flavonoid naturally found in herbs used in traditional medicine. Like many flavonoids, it has potent antioxidant properties.{27237} It also has anti-inflammatory actions related to suppression of signaling through NF-κB in mice.{27240} Galangin acts as an antagonist of the aryl hydrocarbon receptor, inducing apoptosis in cancer cells.{27239,27241,27238} It also inhibits cytochrome P450 isoform 1A1 with an IC50 value of less than 1 µM.{27242}  

 

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Description

A natural flavonoid that has potent antioxidant and anti-inflammatory properties; acts as an antagonist of AhR, inducing apoptosis in cancer cells; also inhibits CYP1A1 with an IC50 value of less than 1 µM

Formal name: 3,5,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one

Synonyms:  3,5,7-Trihydroxyflavone|NSC 407229

Molecular weight: 270.2

CAS: 548-83-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Signaling|NF-κB Signaling||Research Area|Cancer|Transcription Factors|NF-κB||Research Area|Immunology & Inflammation||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Toxicology|Drug Metabolism|Cytochrome P450||Research Area|Toxicology|Drug Metabolism|Xenobiotic Sensing

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