An antifungal compound that is classified as an echinocandin

Caspofungin (acetate) – 5 mg

Brand:
Cayman
CAS:
179463-17-3
Storage:
-20
UN-No:
Non-Hazardous - /

Caspofungin is an antifungal compound that is classified as an echinocandin, as it acts by noncompetititvely inhibiting the enzyme 1,3-β glucan synthase and preventing the synthesis of glucan in the fungal cell wall.{26520} It is effective against disseminated or invasive aspergillosis and candidiasis in mice.{26517,26521} Caspofungin has a 50% minimum effective concentration against Aspergillus spp. of 0.015 µg/ml.{26518} It does not antagonize other antifungal compounds, like amphotericin B, and, in some cases, may show additive or synergistic activity.{26520,26521,20805}  

 

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Description

An antifungal compound that is classified as an echinocandin, as it acts by noncompetititvely inhibiting the enzyme 1,3-β glucan synthase; effective against disseminated or invasive aspergillosis and candidiasis in mice.

Formal name: 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-lornithine]-pneumocandin B0 acetate (1:2)

Synonyms:  L-743,872|MK 0991

Molecular weight: 1,213.40

CAS: 179463-17-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antifungals|Echinocandins||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases|Aspergillosis||Research Area|Infectious Disease|Fungal Diseases|Candidiasis

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