A synthetic CB that selectively targets the peripheral CB2 receptor over the central CB1 receptor (Kis = 7.9 and 1

PF-03550096 – 5 mg

Brand:
Cayman
CAS:
910376-39-5
Storage:
-20
UN-No:
Non-Hazardous - /

PF-03550096 is a synthetic cannabinoid (CB) that selectively targets the peripheral CB2 receptor over the central CB1 receptor (Kis = 7.9 and 1,500 nM for human isoforms, respectively).{28936,28937} It shows similar selectivity for inhibiting forskolin-stimulated cAMP production in CHO cells expressing human CB1 and CB2 receptors (EC50s = 450 and 2.1 nM, respectively).{28937} PF-03550096 is orally bioavailable and significantly reduces colonic pain induced by 2,4,6-trinitrobenzene sulfonic acid in rats.{28937} This product is intended for forensic and research applications.  

 

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Description

A synthetic CB that selectively targets the peripheral CB2 receptor over the central CB1 receptor (Kis = 7.9 and 1,500 nM for human isoforms, respectively)

Formal name: N-[(1S)-1-(aminocarbonyl)-2,2-dimethylpropyl]-2,3-dihydro-3-(3-hydroxy-3-methylbutyl)-2-oxo-1H-benzimidazole-1-carboxamide

Synonyms: 

Molecular weight: 376.5

CAS: 910376-39-5

Purity: ≥98%

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Drugs of Abuse||Research Area|Forensic Chemistry & Toxicology|Cannabinoids|Synthetic Cannabinoids

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