A nitroimidazole with radiosensitizing and antineoplastic properties; metabolites accumulate in hypoxic cells and can themselves be cytotoxic or they can increase the chemosensitivity and radiosensitivity of the target cells; used in the imaging of hypoxic regions in tumors and in the cardiovascular system

Misonidazole – 1 mg

Brand:
Cayman
CAS:
13551-87-6
Storage:
-20
UN-No:
Non-Hazardous - /

Misonidazole is a nitroimidazole with radiosensitizing and antineoplastic properties.{26220} Nitroimidazoles, including misonidazole, specifically accumulate as nitro anion radicals and their metabolites in hypoxic cells.{26220,26221,26223} The metabolites of misonidazole can themselves be cytotoxic or they can increase the chemosensitivity and radiosensitivity of the target cells.{26220} Misonidazole and derivatives, including fluoromisonidazole, are used in the imaging of hypoxic regions in tumors and in the cardiovascular system.{26223,26219,26222}  

 

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Description

A nitroimidazole with radiosensitizing and antineoplastic properties; metabolites accumulate in hypoxic cells and can themselves be cytotoxic or they can increase the chemosensitivity and radiosensitivity of the target cells; used in the imaging of hypoxic regions in tumors and in the cardiovascular system

Formal name: α-(methoxymethyl)-2-nitro-1H-imidazole-1-ethanol

Synonyms:  NSC 261037|Ro 7-0582|SR 1354

Molecular weight: 201.2

CAS: 13551-87-6

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cancer|Cell Death||Research Area|Cancer|Tumor Microenvironment||Research Area|Cardiovascular System|Heart

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