A dual inhibitor of 5-LO and COX pathways

BW 755C – 50 mg

Brand:
Cayman
CAS:
66000-40-6
Storage:
-20
UN-No:
Non-Hazardous - /

BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways, inhibiting 5-LO, COX-1, and COX-2 (IC50s = 0.75 μM, 0.65 μg/ml, and 1.2 μg/ml, respectively).{25336,25335,1287} It may also inhibit other LO pathways in vivo.{67} Through these actions, BW 755C diminishes inflammation.{744,23775}  

 

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Description

A dual inhibitor of 5-LO and COX pathways, inhibiting 5-LO, COX-1, and COX-2 (IC50s = 0.75 μM, 0.65 μg/ml, and 1.2 μg/ml, respectively); may also inhibit other LO pathways in vivo

Formal name: 4,5-dihydro-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-amine

Synonyms: 

Molecular weight: 229.2

CAS: 66000-40-6

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Cyclooxygenases||Product Type|Biochemicals|Small Molecule Inhibitors|Lipoxygenases||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Leukotrienes||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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