A metabolite of the immunosuppressant drug cyclosporin A that displays about 10% lower immunosuppressant activity than cyclosporin A; used as an internal standard for the quantification of cyclosporin A

Cyclosporin D – 1 mg

Brand:
Cayman
CAS:
63775-96-2
Storage:
-20
UN-No:
Non-Hazardous - /

Cyclosporin D is a metabolite of cyclosporin A, an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells.{24989,24993} Cyclosporin D displays about 10% lower immunosuppressant activity than cyclosporin A.{24990,24991} Cyclosporin D has been used as an internal standard for the quantification of cyclosporin A.{24992}  

 

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Description

A metabolite of the immunosuppressant drug cyclosporin A that displays about 10% lower immunosuppressant activity than cyclosporin A; used as an internal standard for the quantification of cyclosporin A

Formal name: 7-L-valine-cyclosporin A

Synonyms: 

Molecular weight: 1,216.70

CAS: 63775-96-2

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Small Molecule Inhibitors|Phosphatases||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Immunosuppressants

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