An antibiotic that competitively inhibits the prokaryotic tryptophanyl-tRNA ligase (IC50 = 30 μM); exhibits antibacterial activity against mupirocin- and fusidic acid-resistant strains of Staphylococci

Indolmycin – 1 mg

Brand:
Cayman
CAS:
21200-24-8
Storage:
-20
UN-No:
Non-Hazardous - /

Indolmycin is an antibiotic isolated from various Streptomyces strains that functions by competitively inhibiting the prokaryotic tryptophanyl-tRNA synthetase (IC50 = 30 μM) without significantly affecting the corresponding eukaryotic synthetase.{24924,24923} It exhibits antibacterial activity against mupirocin- and fusidic acid-resistant strains of Staphylococci.{24922}  

 

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Description

An antibiotic that competitively inhibits the prokaryotic tryptophanyl-tRNA ligase (IC50 = 30 μM); exhibits antibacterial activity against mupirocin- and fusidic acid-resistant strains of Staphylococci

Formal name: 5S-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-4(5H)-oxazolone

Synonyms:  PA 155A|TAK-083

Molecular weight: 257.3

CAS: 21200-24-8

Purity: ≥99%

Formulation: A powder

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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