A plant polyphenol that is classified as a chalcone; a potent antioxidant that affects the numerous pathways modulated by oxidant tone

Butein – 1 mg

Brand:
Cayman
CAS:
487-52-5
Storage:
-20
UN-No:
Non-Hazardous - /

Butein is a plant polyphenol that is classified as a chalcone, due to the propenone linkage between the phenol groups. Like other polyphenols, butein is a potent antioxidant and affects the numerous pathways modulated by oxidant tone, including inflammation, cancer, and immune response.{25061,25058,25057} It inhibits 5-lipoxygenase, the enoyl-acyl-carrier protein reductase of P. falciparum, angiotensin-converting enzyme, and Src kinase (IC50 or Ki values of 0.01, 2.97, 0.73, and 65 μM, respectively).{25060,25062,25056,25063} Butein is also a sirtuin activator, increasing trichostatin A (Item No. 89730)-insensitive deacetylase activity.{12143,20124}  

 

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Description

A plant polyphenol that is classified as a chalcone; a potent antioxidant that affects the numerous pathways modulated by oxidant tone, including inflammation, cancer, and immune response

Formal name: (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one

Synonyms:  2’,3,4,4’-tetrahydroxy Chalcone

Molecular weight: 272.3

CAS: 487-52-5

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|SRC Family||Product Type|Biochemicals|Natural Products|Chalcones||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Activators|Deacetylases||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases|Malaria||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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