An ω-7 fatty acid; dietary administration reduces total body fat

trans-Vaccenic Acid – 500 mg

Brand:
Cayman
CAS:
693-72-1
Storage:
-20
UN-No:
Excepted Quantity - 1170 / 3

trans-Vaccenic acid is an ω-7 fatty acid that has been found in bovine milk fats.{25285} Dietary administration of trans-vaccenic acid (1% w/w) reduces total body fat, mesenteric fat, and adipocyte size, increases inguinal fat mass, and decreases intestinal and hepatic triglyceride secretion in a rat model of obesity with features of metabolic syndrome.{52757} It decreases hepatocellular ballooning and steatosis, markers of non-alcoholic fatty liver disease (NAFLD), in the same model. Dietary administration of a butter enriched with trans-vaccenic acid decreases serum cholesterol levels and the formation of aortic atherosclerotic lesions in Ldlr-/- mice.{25287}  

 

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Description

An ω-7 fatty acid; dietary administration reduces total body fat, mesenteric fat, and adipocyte size, increases inguinal fat mass, and decreases intestinal and hepatic triglyceride secretion in a rat model of obesity with features of metabolic syndrome at 1% w/w; decreases hepatocellular ballooning and steatosis in the same model; dietary administration of a butter enriched with trans-vaccenic acid decreases serum cholesterol levels and the formation of aortic atherosclerotic lesions in Ldlr-/- mice

Formal name: 11E-octadecenoic acid

Synonyms:  trans-11-Octadecenoic acid|C18:1 n-7|C18:1(11E)

Molecular weight: 282.5

CAS: 693-72-1

Purity: ≥95%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Fatty Acids||Product Type|Biochemicals|Lipids|Octadecanoids||Research Area|Cardiovascular System|Cardiovascular Diseases|Atherosclerosis||Research Area|Cardiovascular System|Lipids & Lipoproteins|Lipoproteins||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Metabolic Syndrome||Research Area|Endocrinology & Metabolism|Metabolic Diseases|NAFLD & NASH||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Lipid Biochemistry|Fatty Acids

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