An inhibitor of actin polymerization via inhibition of the Arp2/3 complex; inhibits comet tail formation by L. monocytogenes (IC50 = 7 µM); impairs cell adhesion and spreading

CK 869 – 10 mg

Brand:
Cayman
CAS:
388592-44-7
Storage:
-20
UN-No:
Non-Hazardous - /

CK 869 is an inhibitor of actin polymerization via inhibition of the actin-related protein 2/3 (Arp2/3) complex, leading to reduced cell motility rate and rearrangement of F-actin in M-1 cells.{34274} It inhibits comet tail formation by L. monocytogenes with an IC50 value of 7 µM.{27974} It also impairs cell adhesion and cell spreading in MCF10A human breast epithelial cells.{34273}  

 

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Description

An inhibitor of actin polymerization via inhibition of the Arp2/3 complex; inhibits comet tail formation by L. monocytogenes (IC50 = 7 µM); impairs cell adhesion and spreading

Formal name: 2-(3-bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone

Synonyms:  CK 0157869

Molecular weight: 394.3

CAS: 388592-44-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cell Biology|Cytoskeleton & Motor Proteins||Research Area|Cell Biology|ECM & Adhesion Molecules

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