A potent uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP synthesis by transporting protons across cell membranes

FCCP – 10 mg

Brand:
Cayman
CAS:
370-86-5
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

FCCP is a potent uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP synthesis by transporting protons across cell membranes.{24369,24371} At 40 μM, FCCP induces complete depolymerization of microtubules by increasing intracellular pH via the disruption of the mitochondrial H+ gradient and by decreasing the stability of microtubules by impairing the binding of microtubule-associated proteins.{24370}  

 

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Description

A potent uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP synthesis by transporting protons across cell membranes

Formal name: 2-[2-[4-(trifluoromethoxy)phenyl]hydrazinylidene]-propanedinitrile

Synonyms:  Trifluoromethoxy carbonylcyanide phenylhydrazone

Molecular weight: 254.2

CAS: 370-86-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Oxidative Phosphorylation||Research Area|Cell Biology|Cytoskeleton & Motor Proteins||Research Area|Cell Biology|Mitochondrial Biology

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