An inhibitor of cancer stem cells

ML-243 – 25 mg

Brand:
Cayman
CAS:
1426576-80-8
Storage:
-20
UN-No:
Non-Hazardous - /

ML-243 is an inhibitor of cancer stem cells, displaying 32-fold selective inhibition of a breast cancer stem cell-like cell line (EC50 = 2.0 µM) over a control (mammary epithelial) cell line (EC50 = 64 µM).{24541} It weakly antagonizes the adenosine A2A receptor (IC50 = 10 µM) and has no effect on 68 other targets commonly used in drug discovery for lead profiling.{24541}  

 

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Description

An inhibitor of cancer stem cells, displaying 32-fold selective inhibition of a breast cancer stem cell-like cell line (EC50 = 2.0 µM) over a control (mammary epithelial) cell line (EC50 = 64 µM)

Formal name: (2E)-N-(4,5-dihydro-2-thiazolyl)-3-(4-ethylphenyl)-2-propenamide

Synonyms:  CID-50910523

Molecular weight: 260.4

CAS: 1426576-80-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Cancer|Cancer Stem Cell Research||Research Area|Cell Biology|Stem Cell Research

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