An NNRTI; binds to HIV-1 reverse transcriptase and inhibits RNA plus-strand initiation (IC50 = 0.45 μM); prevents seroconversion and viremia in a chimpanzee model of HIV-1 infection

Nevirapine – 5 mg

Brand:
Cayman
CAS:
129618-40-2
Storage:
-20
UN-No:
Non-Hazardous - /

Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI).{22819} It binds to HIV-1 reverse transcriptase and inhibits RNA plus-strand initiation (IC50 = 0.45 μM). Nevirapine prevents seroconversion and viremia in a chimpanzee model of HIV-1 infection.{49140} Formulations containing nevirapine have been used in combination therapy for the treatment of HIV-1 infection.  

 

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Description

An NNRTI; binds to HIV-1 reverse transcriptase and inhibits RNA plus-strand initiation (IC50 = 0.45 μM); prevents seroconversion and viremia in a chimpanzee model of HIV-1 infection,

Formal name: 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one

Synonyms:  BI-RG 587|NSC 641530|NVP

Molecular weight: 266.3

CAS: 129618-40-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals|Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs)||Product Type|Biochemicals|Small Molecule Inhibitors|Reverse Transcriptases||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS

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