A metabolite of a phosphotidylinositol ether lipid analog known to target the pleckstrin homology domain of Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity

1-O-Octadecyl-2-O-methyl-sn-glycerol – 500 mg

Brand:
Cayman
CAS:
83167-59-3
Storage:
-20
UN-No:
Non-Hazardous - /

1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA). PIAs are known to target the pleckstrin homology domain of the serine/threonine kinase Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity.{24386,24385}  

 

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Description

A metabolite of a phosphotidylinositol ether lipid analog known to target the pleckstrin homology domain of Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity

Formal name: 2S-methoxy-3-(octadecyloxy)-1-propanol

Synonyms:  2-Methyl-1-octadecyl-sn-glycerol|PIA 7

Molecular weight: 358.6

CAS: 83167-59-3

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Glycerolipids||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Signaling|PI3K/Akt/mTOR Signaling||Research Area|Lipid Biochemistry|Glycerolipids

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