A fluorogenic substrate that can be cleaved specifically by caspase-8

Ac-LETD-AFC – 5 mg

Brand:
Cayman
CAS:
210345-02-1
Storage:
-20
UN-No:
Non-Hazardous - /

Ac-LETD-AFC is a fluorogenic substrate that can be cleaved specifically by caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.  

 

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Description

A fluorogenic substrate that can be cleaved specifically by caspase-8

Formal name: N-acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine

Synonyms:  Caspase-8 Substrate (Fluorogenic)|N-Acetyl-Leu-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin

Molecular weight: 729.7

CAS: 210345-02-1

Purity: ≥95%

Formulation: A crystalline solid

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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