The 4-oxo derivative of TEMPO; possible uses as a spin trap

TEMPONE – 1 g

Brand:
Cayman
CAS:
2896-70-0
Storage:
-20
UN-No:
Non-Hazardous - /

2,2,6,6-Tetramethylpiperidin-1-oxyl (TEMPO) is a stable radical that will react with reactive oxygen species (ROS).{15948} This conversion, followed by ESR, provides an indirect way to monitor ROS production in biological systems. TEMPONE is the 4-oxo derivative of TEMPO. In addition to possible uses as a spin trap, this nitroxyl radical can be used in hydrogen transfer experiments and as a polarizing agent in dynamic nuclear polarization NMR spectroscopy.{24287,24289} TEMPONE and other nitroxyl radicals have also been shown to reduce mean arterial pressure in spontaneously hypertensive rats when administered intravenously.{24288}  

 

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Description

The 4-oxo derivative of TEMPO; possible uses as a spin trap, in hydrogen transfer experiments, and as a polarizing agent in dynamic nuclear polarization NMR spectroscopy

Formal name: 2,2,6,6-tetramethyl-4-oxo-1-piperidinyloxy

Synonyms:  4-oxo-TEMPO|Triacetoneamine nitroxide

Molecular weight: 170.2

CAS: 2896-70-0

Purity: ≥98%

Formulation: A crystalline solid

Application|EPR/ESR||Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Product Type|Biochemicals|Ox Stress Reagents|Spin Traps||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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