17-phenyl trinor PGE2 is a synthetic analog of PGE2. It is an EP1 and EP3 receptor agonist.{3318

17-phenyl trinor Prostaglandin E2 – 1 mg

Brand:
Cayman
CAS:
38315-43-4
Storage:
-20
UN-No:
Non-Hazardous - /

17-phenyl trinor PGE2 is a synthetic analog of PGE2. It is an EP1 and EP3 receptor agonist.{3318,1025} 17-phenyl trinor PGE2 causes contraction of the guinea pig ileum at a concentration of 11 µM.{3318} It is slightly less potent than PGE2 in stimulating gerbil colon and rat uterus.{1025} With an ED50 value of 350 µg/kg, 17-phenyl trinor PGE2 is 4.4 times more potent than PGE2 as an antifertility agent in hamsters.{1025}  

 

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Description

17-phenyl trinor PGE2 is a synthetic analog of PGE2. It is an EP1 and EP3 receptor agonist.{3318,1025} 17-phenyl trinor PGE2 is an EP1 and EP3 receptor agonist.1,2 It causes contraction of the guinea pig ileum at a concentration of 11 µM.{3318} It is slightly less potent than PGE2 in stimulating gerbil colon and rat uterus.{1025} With an ED50 value of 350 µg/kg, 17-phenyl trinor PGE2 is 4.4 times more potent than PGE2 as an antifertility agent in hamsters.{1025}

Formal name: 9-oxo-11α,15S-dihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid

Synonyms:  17-phenyl trinor PGE2

Molecular weight: 386.5

CAS: 38315-43-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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