An isothiocyanate derived from glucoraphanin; powerful antioxidant

L-Sulforaphane – 5 mg

Brand:
Cayman
CAS:
142825-10-3
Storage:
-20
UN-No:
De Minimis - 1170 / 3

L-Sulforaphane is an isothiocyanate derived from the natural compound glucoraphanin, which is abundant in cruciferous vegetables, including broccoli.{23486} It has powerful antioxidant, anti-inflammatory, and anti-carcinogenic effects.{23486,23487} L-Sulforaphane, at 40 µM, activates nuclear factor erythroid 2-related factor 2- (Nrf2) mediated gene expression by disrupting its association with Kelch-like ECH-associated protein 1 (Keap1), allowing Nrf2 to enter the nucleus to alter transcription.{21883,21473} In this way, sulforaphane induces the expression of phase II detoxification enzymes, which in turn provide diverse beneficial effects.{21884,23486}  

 

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Description

An isothiocyanate derived from glucoraphanin; powerful antioxidant, anti-inflammatory, and anti-carcinogenic effects; at 40 µM, activates Nrf2-mediated gene expression of phase II detoxification enzymes by disrupting the Keap1-Nrf2 complex, allowing Nrf2 to alter transcription

Formal name: 1-isothiocyanato-4-[(R)-methylsulfinyl]-butane

Synonyms:  (R)-Sulforaphane

Molecular weight: 177.3

CAS: 142825-10-3

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Activators|Transcription Factors & Coactivators||Research Area|Immunology & Inflammation||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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