15(R)-PGE2 is the C-15 epimer of the naturally occurring 15(S)-PGE2. 15(R)-PGE2 is much less potent than the natural stereoisomer in most biological assays. In hamsters

15(R)-Prostaglandin E2 – 5 mg

Brand:
Cayman
CAS:
38873-82-4
Storage:
-20
UN-No:
De Minimis - 1231 / 3

15(R)-Prostaglandin E2 (15(R)-PGE2) is the C-15 epimer of the naturally occurring 15(S)-PGE2. 15(R)-PGE2 is much less potent than the natural stereoisomer in most biological assays. In hamsters, a dose of 0.20 mg of PGE2 (Item No. 14010) inhibits fertility by 100%, whereas a dose of 1.0 mg of 15(R)-PGE2 inhibits fertility by only 17%.{1925} 15(R)-PGE2 occurs as a minor impurity in some pharmaceutical formulations of PGE2 used in obstetrics.  

 

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Description

15(R)-PGE2 is the C-15 epimer of the naturally occurring 15(S)-PGE2. 15(R)-PGE2 is much less potent than the natural stereoisomer in most biological assays. In hamsters, a dose of 0.20 mg of PGE2 inhibits fertility by 100%, whereas a dose of 1.0 mg of 15(R)-PGE2 inhibits fertility by only 17%.{1925} 15(R)-PGE2 occurs as a minor impurity in some pharmaceutical formulations of PGE2 used in obstetrics.

Formal name: 9-oxo-11α,15R-dihydroxy-prosta-5Z,13E-dien-1-oic acid

Synonyms:  15(R)-PGE2|15-epi PGE2

Molecular weight: 352.5

CAS: 38873-82-4

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Pharmaceutical Impurities||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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