An endogenous intermediate in the synthesis of phosphatidylcholine that demonstrates protective effects in cerebral ischemia

Citicoline (sodium salt) – 100 mg

Brand:
Cayman
CAS:
33818-15-4
Storage:
-20
UN-No:
Non-Hazardous - /

Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine, the major phospholipid in eukaryotic cells.{23421} It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicholine demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders.{23420} Exogenous administration of citicholine to rodents (500 mg/kg i.p. immediately after ischemia and at 3-h reperfusion) has been shown to stimulate the synthesis of phosphatidylcholine, sphingomyelin, and cardiolipin and to attenuate the release of arachidonic acid and the accumulation of ceramide.{23419}  

 

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Description

An endogenous intermediate in the synthesis of phosphatidylcholine that demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders when administered exogenously

Formal name: P’-[2-(trimethylammonio)ethyl] ester-cytidine 5′-(trihydrogen diphosphate)-inner, monosodium salt

Synonyms:  Cytidine 5′-diphosphocholine|Flussorex|Gerolin|Logan|Neurotron|Sinkron

Molecular weight: 510.3

CAS: 33818-15-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cardiovascular System|Cardiovascular Diseases|Stroke||Research Area|Lipid Biochemistry|Glycerophospholipids||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Neuroscience|Neuroprotection|Ischemia

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