A cell-trappable fluorogenic probe for the detection of H2S; reaction of the azide moieties with H2S in buffers or live cells leads to generation of carboxamide rhodamine 110

SF7-AM – 1 mg

Brand:
Cayman
CAS:
1416872-50-8
Storage:
-20
UN-No:
Non-Hazardous - /

SF7-AM is a cell-trappable fluorogenic probe for the detection of hydrogen sulfide (H2S).{22867} Following entry into cells, cleavage of the acetoxymethyl ester groups by intracellular esterases results in an anionic charge, trapping the probe inside the cells.{52040} Reaction of the azide moieties with H2S in buffers or live cells leads to generation of carboxamide rhodamine 110, which displays excitation/emission maxima of 498/526 nm, respectively.{22867}  

 

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Description

A cell-trappable fluorogenic probe for the detection of H2S; reaction of the azide moieties with H2S in buffers or live cells leads to generation of carboxamide rhodamine 110, which displays ex/em maxima of 498/526 nm, respectively

Formal name: N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[(3′,6′-diazido-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthen]-5-yl)carbonyl]-glycine, (acetyloxy)methyl ester

Synonyms:  Sulfidefluor-7 acetoxymethyl ester

Molecular weight: 685.6

CAS: 1416872-50-8

Purity: ≥95%

Formulation: A crystalline solid

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Research Area|Oxidative Stress & Reactive Species|Reactive Sulfur|H2S

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