A competitive

DNQX – 25 mg

Brand:
Cayman
CAS:
2379-57-9
Storage:
-20
UN-No:
Non-Hazardous - /

DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively versus IC50 = 40 μM for NMDA receptors).{23070,23071,23072} This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus.{23069}  

 

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Description

A competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively versus IC50 = 40 μM for NMDA receptors); used to target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors

Formal name: 1,4-dihydro-6,7-dinitro-2,3-quinoxalinedione

Synonyms:  6,7-Dinitroquinoxaline-2,3-dione|FG 9041

Molecular weight: 252.1

CAS: 2379-57-9

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Research Area|Neuroscience

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