11-deoxy-16

11-deoxy-16,16-dimethyl Prostaglandin E2 – 5 mg

Brand:
Cayman
CAS:
53658-98-3
Storage:
-20
UN-No:
De Minimis - 1231 / 3

11-deoxy-16,16-dimethyl PGE2 is a stable synthetic analog of PGE2. It is an agonist for both EP2 and EP3 receptors.{3620} It is an effective inhibitor of gastric acid secretion and ulcer formation in the rat, with ED50 values of 1 mg/kg and 0.021 mg/kg respectively.{1147} It is 900 times more potent than PGF2α in the contraction of human respiratory tract smooth muscle in vitro.{2218}  

 

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Description

11-deoxy-16,16-dimethyl PGE2 is a stable synthetic analog of PGE2. It is an agonist for both EP2 and EP3 receptors.{3620} It is an effective inhibitor of gastric acid secretion and ulcer formation in the rat, with ED50 values of 1 mg/kg and 0.021 mg/kg respectively.{1147} It is 900 times more potent than PGF2α in the contraction of human respiratory tract smooth muscle in vitro.{2218}

Formal name: 9-oxo-15R-hydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid

Synonyms:  11-deoxy-16,16-dimethyl PGE2

Molecular weight: 364.5

CAS: 53658-98-3

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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