An adenylyl cyclase inhibitor that can also inhibit cAMP and cGMP phosphodiesterases and block slow extracellular and store-operated Ca2+ entry into cells; blocks voltage-dependent K+ channels

MDL 12330A (hydrochloride) – 5 mg

Brand:
Cayman
CAS:
40297-09-4
Storage:
-20
UN-No:
Non-Hazardous - /

MDL 12330A is an adenylyl cyclase inhibitor that can also inhibit cAMP and cGMP phosphodiesterases and block slow extracellular and store-operated Ca2+ entry into cells. It is widely used to investigate the role of the adenylyl cyclase/cAMP signaling pathway. MDL 12330A has also been reported to block voltage-dependent K+ channels, extend action potential duration, and enhance insulin secretion in pancreatic β-cells.{32913}  

 

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Description

An adenylyl cyclase inhibitor that can also inhibit cAMP and cGMP phosphodiesterases and block slow extracellular and store-operated Ca2+ entry into cells; blocks voltage-dependent K+ channels, extends action potential duration, and enhances insulin secretion in pancreatic β-cells

Formal name: rel-N-[(1R,2R)-2-phenylcyclopentyl]-azacyclotridec-1-en-2-amine, monohydrochloride

Synonyms:  RMI 12330A

Molecular weight: 377

CAS: 40297-09-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Product Type|Biochemicals|Small Molecule Inhibitors|Phosphodiesterases||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes

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