A channel blocker that acts on several TRP channels

N-(p-amylcinnamoyl) Anthranilic Acid – 250 mg

Brand:
Cayman
CAS:
110683-10-8
Storage:
-20
UN-No:
Non-Hazardous - /

N-(p-amylcinnamoyl) Anthranilic acid (ACA) is a channel blocker that acts on several transient receptor potential (TRP) channels, including TRPM2, TRPM8, and TRPC6 (IC50 = 1.7, 3.8, and 2.3 μM, respectively).{24045,24047} It is a weak inhibitor of TRPV1.{24047} ACA is also an inhibitor of phospholipase A2, blocking the release of arachidonic acid when given at 50 μM.{24044,24046}  

 

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Description

A channel blocker that acts on several TRP channels, including TRPM2, TRPM8, and TRPC6 (IC50 = 1.7, 3.8, and 2.3 μM, respectively); inhibits PLA2, blocking the release of arachidonic acid when given at 50 μM

Formal name: 2-[[1-oxo-3-(4-pentylphenyl)-2-propen-1-yl]amino]-benzoic acid

Synonyms:  ACA

Molecular weight: 337.4

CAS: 110683-10-8

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Phospholipases||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases

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