TBB – 50 mg

Brand:
Cayman
CAS:
17374-26-4
Storage:
-20
UN-No:
Non-Hazardous - /

TBB is an ATP/GTP-competitive inhibitor of casein kinase 2 (CK2; IC50 = 0.15 µM for rat liver CK2).{22897} It also inhibits PIM3 and DYRK2 with IC50 values of 0.86 and 0.99 µM, respectively, and several other protein kinases with IC50 values in the low micromolar range but displays less than 10% inhibition at 26 additional kinases up to 10 µM.{22896,22897}  

 

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Description

An inhibitor of CK2 (IC50 = 0.15 µM); inhibits PIM3 and DYRK2 (IC50s = 0.86 and 0.99 µM, respectively) and other protein kinases with IC50 values in the low micromolar range but displays less than 10% inhibition at 26 additional kinases up to 10 µM ,


Formal name: 4,5,6,7-tetrabromo-1H-benzotriazole

Synonyms:  NSC 231634|Tetrabromobenzotriazole

Molecular weight: 434.7

CAS: 17374-26-4

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Kinase Inhibitors|CK2||Product Type|Biochemicals|Kinase Inhibitors|Other Non-Receptor Tyrosine Kinases||Product Type|Biochemicals|Kinase Inhibitors|Other Serine/Threonine Kinases||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area