A fluorescent indole alkaloid extracted from B. caapi that inhibits MAO-A and MAO-B with much weaker potency (IC50s = 74 nM and >100 μM

tetrahydro-Harmine – 25 mg

Brand:
Cayman
CAS:
17019-01-1
Storage:
-20
UN-No:
Non-Hazardous - /

tetrahydro-Harmine (THH) is a fluorescent indole alkaloid extracted from B. caapi, a woody vine that is used to produce a psychoactive beverage, ayahuasca, which has been ritually ingested for medicoreligious purposes throughout South America since pre-Columbian times.{24007} THH inhibits monoamine oxidase (MAO)-A and MAO-B with much weaker potency (IC50s = 74 nM and >100 μM, respectively) compared to the companion harmala alkaloids also found in B. caapi: harmaline (Item No. 10995; IC50s = 2.5 nM and 25 μM, respectively) and harmine (Item No. 10010324; IC50s = 2 nM and 20 μM, respectively).{24009,24008}  

 

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Description

A fluorescent indole alkaloid extracted from B. caapi that inhibits MAO-A and MAO-B with much weaker potency (IC50s = 74 nM and >100 μM, respectively) compared to its companion harmala alkaloids: harmaline (IC50s = 2.5 nM and 25 μM, respectively) and harmine (IC50s = 2 nM and 20 μM, respectively)

Formal name: 2,3,4,9-tetrahydro-7-methoxy-1-methyl-1H-pyrido[3,4-b]indole

Synonyms:  Leptaflorine|THH

Molecular weight: 216.3

CAS: 17019-01-1

Purity: ≥98%

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Drugs of Abuse||Research Area|Forensic Chemistry & Toxicology

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