8-iso PGE2 isopropyl ester is a more lipophilic form of the free acid

8-iso Prostaglandin E2 isopropyl ester – 5 mg

Brand:
Cayman
CAS:
330589-21-4
Storage:
-20
UN-No:
De Minimis - 1170 / 3

8-iso PGE2 isopropyl ester is a more lipophilic form of the free acid, 8-iso PGE2. Prostaglandin esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of prostaglandins show greatly diminished agonist activity in vitro compared to the parent free acids.  

 

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Description

8-iso PGE2 isopropyl ester is a more lipophilic form of the free acid, 8-iso PGE2. Prostaglandin esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of prostaglandins show greatly diminished agonist activity in vitro compared to the parent free acids.

Formal name: 9-oxo-11α,15S-dihydroxy-(8β)-prosta-5Z,13E-dien-1-oic acid, isopropyl ester

Synonyms:  8-iso PGE2 isopropyl ester

Molecular weight: 394.6

CAS: 330589-21-4

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Isoprostanes||Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Reactive O2/N2 Pathways||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation

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