A polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release

Ruthenium Red – 250 mg

Brand:
Cayman
CAS:
11103-72-3
Storage:
-20
UN-No:
Non-Hazardous - /

Ruthenium red is a polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release, blocks Ca2+ uptake and release from mitochondria, and prevents Ca2+ release from ryanodine-sensitive intracellular stores in skeletal and cardiac muscle (Kis = 16 nM – 5.9 μM, depending on Ca2+ concentration).{22566} Additionally, ruthenium red binds to anionic sites of cellular components, predominantly to surface glycoconjugates, and can be used as a marker of negative binding sites related to cellular transport, barrier, or receptor functions.{22567}  

 

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Description

A polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release, blocks Ca2+ uptake and release from mitochondria, and prevents Ca2+ release from ryanodine-sensitive intracellular stores in skeletal and cardiac muscle (Kis = 16 nm – 5.9 μM, depending on Ca2+ concentration)

Formal name:

Synonyms:  Ammoniated Ruthenium Oxychloride|C.I. 77800

Molecular weight: 786.4

CAS: 11103-72-3

Purity:

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Cell Biology|Mitochondrial Biology

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