A broad-spectrum antibiotic used in cell culture systems as a selective agent for cells harboring the bacterial tetR gene

Tetracycline (hydrochloride) – 25 g

Brand:
Cayman
CAS:
64-75-5
Storage:
-20
UN-No:
Non-Hazardous - /

Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site.{22680} It is used in cell biology as a selective agent in cell culture systems. Tetracycline is toxic to prokaryotic and eukaryotic cells and selects for cells harboring the bacterial tetR gene, which are resistant to the antibiotic.{17511}  

 

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Description

A broad-spectrum antibiotic used in cell culture systems as a selective agent for cells harboring the bacterial tetR gene, which are resistant to the antibiotic

Formal name: (4S,4aS,5aS,6S,12aS)- 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide, monohydrochloride

Synonyms: 

Molecular weight: 480.9

CAS: 64-75-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Tetracyclines||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis

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