An aminocyclitol antibiotic active against Gram-negative and Gram-positive bacteria; inhibits protein synthesis by binding to the 30S ribosomal subunit and interfering with peptidyl tRNA translocation

Spectinomycin (hydrochloride hydrate) – 1 g

Brand:
Cayman
CAS:
22189-32-8
Storage:
-20
UN-No:
Non-Hazardous - /

Spectinomycin is an aminocyclitol antibiotic produced by S. spectabilis that is active against Gram-negative and Gram-positive bacteria. Spectinomycin inhibits protein synthesis by binding to the 30S ribosomal subunit and interfering with peptidyl tRNA translocation.{22690} Mutations in the gene for ribosomal protein S5 prevents binding of spectinomycin and contributes to bacterial resistance.{22691}  

 

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Description

An aminocyclitol antibiotic active against Gram-negative and Gram-positive bacteria; inhibits protein synthesis by binding to the 30S ribosomal subunit and interfering with peptidyl tRNA translocation

Formal name: (5aR,9aR,10aS)-decahydro-4aR,7S,9S-trihydroxy-2R-methyl-6S,8R-bis(methylamino)-4H-pyrano[3-b][1,4]benzodioxin-4-one, dihydrochloride pentahydrate

Synonyms: 

Molecular weight: 495.4

CAS: 22189-32-8

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Aminoglycosides||Product Type|Biochemicals|Natural Products||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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