A flavonoid isolated from the root of the traditional Chinese herb S. baicalensis with anti-inflammatory

Wogonin – 5 mg

Brand:
Cayman
CAS:
632-85-9
Storage:
-20
UN-No:
Non-Hazardous - /

Wogonin is an O-methylated flavonoid isolated from the root of the traditional Chinese herb S. baicalensis with anti-inflammatory, antioxidant, and neuroprotective activities.{22361} At concentrations of 5-50 μM, wogonin inhibits inflammatory activation of cultured brain microglia by diminishing LPS-induced TNF-α, IL-1β, and nitric oxide production.{22362} Wogonin at 75 μM demonstrates tumor therapeutic potential inducing sub-G1 phase apoptosis through activation of caspase-3 activity in human osteocarcinoma cell lines.{22360}  

 

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Description

A flavonoid isolated from the root of the traditional Chinese herb S. baicalensis with anti-inflammatory, antioxidant, antitumor, and neuroprotective activities at concentrations from 5-75 μM

Formal name: 5,7-dihydroxy-8-methoxy-2-phenyl-4H-1-benzopyran-4-one

Synonyms:  BRN 0287152

Molecular weight: 284.3

CAS: 632-85-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Neuroscience|Neuroprotection||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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