A potent agonist of D2 receptors (Ki = 5.8 nM); has neuroprotective and regenerative effects in animal models of Parkinson’s disease

B-HT 920 (hydrochloride) – 5 mg

Brand:
Cayman
CAS:
36085-73-1
Storage:
-20
UN-No:
Non-Hazardous - /

B-HT 920 is a potent agonist of dopamine 2 (D2) receptors (Ki = 5.8 nM) that shows selectivity for D2 over D3 and D4 receptors.{34094,34095,34098} It has neuroprotective and regenerative effects in animal models of Parkinson’s disease.{34093} B-HT 920 is also an agonist of α2-adrenergic receptors and an antagonist of serotonin-3 (5-HT3; Ki = 0.35 µM) receptors.{34096,34097}  

 

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Description

A potent agonist of D2 receptors (Ki = 5.8 nM); has neuroprotective and regenerative effects in animal models of Parkinson’s disease

Formal name: 5,6,7,8-tetrahydro-6-(2-propen-1-yl)-4H-thiazolo[4,5-d]azepin-2-amine, dihydrochloride

Synonyms: 

Molecular weight: 282.2

CAS: 36085-73-1

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Neurodegenerative Disorders|Parkinson’s Disease||Research Area|Neuroscience|Neuroprotection

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