A natural product with anti-inflammatory

Indirubin – 10 mg

Brand:
Cayman
CAS:
479-41-4
Storage:
-20
UN-No:
Non-Hazardous - /

Indirubin is a natural product originally extracted from roots and leaves of the Indigo plant (I. tinctoria) used in traditional Chinese medicine for anti-inflammatory, anti-tumor, and neuroprotective effects. Indirubin inhibits glycogen synthase kinase-3 (IC50 = 2.5 μM) and cyclin-dependent kinases 1 and 5 (IC50 = 10 μM for both isoforms).{22470,22471,22472}  

 

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Description

A natural product with anti-inflammatory, anti-tumor, and neuroprotective effects; inhibits GSK-3 (IC50 = 2.5 μM) and Cdk1 and 5 (IC50 = 10 μM for both isoforms)

Formal name: 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one

Synonyms:  C.I. 73200|Couroupitine B|Indigopurpurin|NSC 105327

Molecular weight: 262.3

CAS: 479-41-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|GSK3||Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Cycle||Research Area|Cell Biology|Cell Signaling||Research Area|Neuroscience|Neuroprotection

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