A coumarin derived from citrus plants with anti-inflammatory

Auraptene – 5 mg

Brand:
Cayman
CAS:
495-02-3
Storage:
-20
UN-No:
Non-Hazardous - /

Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities.{21870,21869,21867,21868,21871} It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis.{21870} When examined for its potential use in Alzheimer’s disease treatment, auraptene was shown to inhibit β-secretase (BACE1) activity with an IC50 value of 345.1 μM.{21872}  

 

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Description

A coumarin derived from citrus plants with anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities; inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis

Formal name: 7-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-2H-1-benzopyran-2-one

Synonyms:  7-Geranyloxycoumarin

Molecular weight: 298.4

CAS: 495-02-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Coumarins||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease||Research Area|Neuroscience|Neuroprotection

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