A purine analog with immunosuppressive effects; serves as a prodrug for 6-mercaptopurine

Azathioprine – 1 g

Brand:
Cayman
CAS:
446-86-6
Storage:
-20
UN-No:
Non-Hazardous - /

Azathioprine is a purine analog with immunosuppressive effects.{21835} It serves as a prodrug for 6-mercaptopurine, which alters purine processing and DNA synthesis, interfering with the proliferation of lymphocytes and other myeloid cells.{21835,21834} Its immunomodulating actions are used to benefit inflammatory bowel disease, as well as a wide range of additional diseases with immunological or autoimmunological components, including rheumatoid arthritis and lupus nephritis.{21835,21834,21833}  

 

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Description

A purine analog with immunosuppressive effects; serves as a prodrug for 6-mercaptopurine, which alters purine processing and DNA synthesis, interfering with lymphocyte proliferation; used to benefit IBD, as well as additional diseases with immunological or autoimmunological components

Formal name: 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine

Synonyms:  Azamune|Azoran|BW 57-322|Imuran|NSC 39084

Molecular weight: 277.3

CAS: 446-86-6

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Immunology & Inflammation|Autoimmunity|Lupus||Research Area|Immunology & Inflammation|Autoimmunity|Rheumatoid Arthritis||Research Area|Immunology & Inflammation|Gastric Disease|IBS||Research Area|Immunology & Inflammation|Immunosuppressants||Research Area|Immunology & Inflammation|Innate Immunity

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