19(R)-hydroxy Prostaglandin E1 – 500 µg

Brand:
Cayman
CAS:
64625-55-4
Storage:
-20
UN-No:
De Minimis - 1170 / 3

19(R)-hydroxy PGE1 is the major prostaglandin found in the semen of primates, including man. It is an agonist for the EP1 and EP3 receptor subtypes, and exhibits contractile activity on smooth muscle preparations.{427,1441} It has an EC50 of 320 nM for contracting guinea pig ileum, which express EP1 receptors, and an EC50 of 80 nM for contracting chick ileum, which express EP3 receptors.{1441}  

 

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Description

19(R)-hydroxy PGE1 is the major prostaglandin found in the semen of primates, including man. It is an agonist for the EP1 and EP3 receptor subtypes, and exhibits contractile activity on smooth muscle preparations.{427,1441} It has an EC50 of 320 nM for contracting guinea pig ileum, which express EP1 receptors, and an EC50 of 80 nM for contracting chick ileum, which express EP3 receptors.{1441}


Formal name: 9-oxo-11α,15S,19R-trihydroxy-prost-13E-en-1-oic acid

Synonyms:  19(R)-hydroxy PGE1

Molecular weight: 370.5

CAS: 64625-55-4

Purity: ≥95%

Formulation: A solution in ethanol


Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway