A prodrug form of ganciclovir; increases survival and reduces weight loss in an immunosuppressed hamster model of disseminated Ad5 infection at 200 mg/kg

Valganciclovir (hydrochloride) – 10 mg

Brand:
Cayman
CAS:
175865-59-5
Storage:
-20
UN-No:
Non-Hazardous - /

Valganciclovir is a valyl ester prodrug form of the antiviral nucleoside analog ganciclovir (Item No. 13853). In vivo, valganciclovir (200 mg/kg) increases survival and reduces weight loss in an immunosuppressed hamster model of disseminated adenovirus type 5 (Ad5) infection.{52613} Formulations containing valganciclovir have been used in the prevention of post-transplant cytomegalovirus (CMV) infections.  

 

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Description

A prodrug form of ganciclovir; increases survival and reduces weight loss in an immunosuppressed hamster model of disseminated Ad5 infection at 200 mg/kg

Formal name: 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester L-valine, monohydrochloride

Synonyms:  Ro 107-9070/194

Molecular weight: 390.8

CAS: 175865-59-5

Purity: ≥95%

Formulation: A crystalline solid

Application||Product Type|Biochemicals|Antivirals||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Infectious Disease|Viral Diseases

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